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Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications [electronic resource] : Proceedings of the 6th International Conference on Sodium Calcium Exchange / edited by Lucio Annunziato
Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications [electronic resource] : Proceedings of the 6th International Conference on Sodium Calcium Exchange / edited by Lucio Annunziato
Estensione 1 online resource (XXIV, 463 p).
Disciplina 612.8
Accesso persona Annunziato, Lucio
Accesso ente SpringerLink (Online service)
ISBN 9781461447566
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I. Historical Perspective -- 1. Livin with NCX and Lovin It: 45 Year Romance -- 2. 20 Years from NCX Purification and Cloning: Milestones -- Part II Structural and Functional Aspects of NCX -- 3. Ca2+ Regulation in the Na+/Ca2+ Exchanger Features a Dual Electrostatic Switch Mechanism -- 4. Molecular Determinants of Allosteric Regulation in NCX Proteins -- 5. NCX1: Mechanism of Transport -- 6. Structural Studies of the Ca2+ Regulatory Domain of Drosophila Na+/Ca2+ Exchanger CALX -- 7. Interplay of Ca2+ and Mg2+ in Sodium-Calcium and in other Ca2+ Binding Proteins. Magnesium: Watchdog That Blocks Each Turn If Able -- Part III. Structural and Functional Aspects of NCKX -- 8. Functional and Structural Properties of the NCKX2 Na+-Ca2+/K+ Exchanger: a Comparison with the NCX1 Na+/Ca2+ Exchanger -- 9. NCKX5, a Natural Regulator of Human Skin Colour Variation Regulates the Expression of Key Pigment Genes mc1r and alpha-MSH, and Alters Cholesterol Homeostasis in Normal Human Melanocytes -- 10. Expression and Regulation of Sodium/Calcium Exchangers, NCX and NCKX, in Reproductive Tissues: Do They Play a Critical Role in Calcium Transport for Reproduction and Development? -- Part IV. Genetic and Epigenetic Regulation -- 11. Transcriptional Pathways and Potential Therapeutic Targets in the Regulation of NCX1 Expression in Cardiac Hypertrophy and Failure -- 12. Transcriptional Regulation of ncx1 Gene in the Brain -- Part V. Regulatory Mechanisms of NCX -- 13. Metabolic Regulation of the Squid Nerve Na+/Ca2+ Exchanger: Recent Developments -- 14. Regulation of Sodium-Calcium Exchanger Activity by Creatine Kinase -- 15. Coordinated Regulation of Cardiac Na<+/Ca2+ Exchanger and Na+-K+-ATPase by Phospholemman (FXYD1) -- Part VI. Subcellular Localization and Function of NCX in Ca2+-Storing Organelles and Mitochondria -- 16. Mitochondria Na+-Ca2+ Exchange in Cardiomyocytes and Lymphocytes -- 17. New Insights in Mitochondrial Calcium Handling by Sodium/Calcium Exchanger -- Part VII. NCX in Neurodegenerative Diseases -- 18. Genetically-Modified Mice as a Strategy to Unravel the Role Played by the Na+/Ca2+ Exchanger in Brain Ischemia and in Spatial Learning and Memory Deficits -- 19. NCX as a Key Player in the Neuroprotection Exerted by Ischemic Preconditioning and Postconditioning -- 20. The Role of the Mitochondrial NCX in the Mechanism of Neurodegeneration in Parkinson’s Disease -- 21. The Contribution of the Sodium-Calcium Exchanger (NCX) and Plasma Membrane Ca2+-ATPase (PMCA) to Cerebellar Synapse Function -- Part VIII. Emerging Role of NCX Activity in Immune and Glial Cells -- 22. Sodium-Calcium Exchanger Modulates the L-Glutamate Ca2+-signalling in Type-1 Cerebellar Astrocytes -- 23. Immunosupressive Drugs, Immunophilins and Functional Expression of NCX Isoforms -- 24. Calcium Influx Through Reversed ncx Controls Migration Of Microglia -- 25. Sodium Fluxes and Astroglial Function -- 26. New Roles of NCX in Glial Cells: Activation Of Microglia in Ischemia and Differentiation of Oligodendrocytes -- 27. Human Macrophages and Monocytes Express Functional Na+/Ca2+ Exchangers 1 and 3 -- Part IX. NCX in the Hearth and Vascular Smooth Muscle -- 28. New Insights into the Contribution of Arterial NCX to the Regulation of Myogenic Tone and Blood Pressure -- 29. Toward an Understanding of the Complete NCX1 Lifetime in the Cardiac Sarcolemma -- Part X. NCX Role in Hypertension, Heart Failure, Ischemia-Reperfusion, Arrhythmias, and Diabetes -- 30. Cardiac Sodium-Calcium Exchange and Efficient Excitation-Contraction Coupling: Implications for Heart Disease -- 31. Cross-talk Between Plasma Membrane Na+/Ca2+ Exchanger-1 and TRPC/ORAI Containing Channels: Key Players in Arterial Hypertension -- 32. T-tubule Remodeling and Ryanodine Receptor Organization Modulate Sodium-Calcium Exchange -- 33. Na+/ Ca2+ Exchange and the Plasma Membrane Ca2+-ATPase in β-Cell Function and Diabetes -- Part XI. NCX Partners in Ionic Homeostasis: ASIC, NMDA, NHE, and TRPC -- 34. The Na+/H+ Exchanger NHE5 is Sorted to Discrete Intracellular Vesicles in the Central and Peripheral Nervous Systems -- 35. The Role of Na+/H+ Exchanger Isoform 1 in Inflammatory Responses: Maintaining H+ Homeostasis of Immune Cells -- 36. Acid-sensing Ion Channels in Pathological Conditions -- 37. Non-Selective Cation Channels and Links to Hippocampal Ischemia, Aging and Dementia.
Record Nr. YALE-13630385
Materiale a stampa
Lo trovi qui: Yale University
Epigenetic Methods in Neuroscience Research [electronic resource] / edited by Nina Karpova
Epigenetic Methods in Neuroscience Research [electronic resource] / edited by Nina Karpova
Edizione [1st ed. 2016.]
Estensione 1 online resource (XII, 258 p.) 43 illus., 37 illus. in color.
Disciplina 612.8
Accesso persona Karpova, Nina.editor.
Accesso ente SpringerLink (Online service)
ISBN 9781493927548
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Epigenetics: From Basic Biology To Chromatin Modifying Drugs And New Potential Clinical Applications -- Analysis Of Brain Epigenome: A Guide To Epigenetic Methods -- Analysis Of DNA Methylation By Bisulfite Reaction In Neural Cells As An Example Of Orexin Neurons -- Protocol For The Simultaneous Analysis Of Gene DNA Methylation And Mrna Expression Levels In The Rodent Brain -- Simultaneous Quantification Of Global 5mc And 5hmc Levels In The Nervous System Using A HPLC/MS Method -- Protocol For Methylated DNA Immunoprecipitation (Medip) Analysis -- Cell Type–Specific DNA Methylation Analysis In Neurons And Glia -- Immunohistochemical Detection Of Oxidized Forms Of 5-Methylcytosine In Embryonic And Adult Brain Tissue -- Analysis Of Histone Modifications In Neural Cells As An Example Of Orexin Neurons -- Site-Specific Delivery Of Epigenetic Modulating Drugs Into The Rat Brain -- Mammalian Genome Plasticity: Expression Analysis Of Transposable Elements -- Tools For Analyzing The Role Of Local Protein Synthesis In Synaptic Plasticity -- In Situ Detection Of Neuron-Specific Micrornas In Frozen Brain Tissue Meister -- Protocol For High-Throughput Mirna Profiling Of The Rat Brain -- Metabolites As Clock Hands: Estimation Of Internal Body Time Using Blood Metabolomics.
Record Nr. YALE-13712713
Materiale a stampa
Lo trovi qui: Yale University
RNA Metabolism in Neurodegenerative Diseases [electronic resource] / edited by Rita Sattler, Christopher J. Donnelly
RNA Metabolism in Neurodegenerative Diseases [electronic resource] / edited by Rita Sattler, Christopher J. Donnelly
Estensione XX, 310 p. 34 illus. in color : online resource.
Disciplina 612.8
Accesso persona Sattler, Rita
Donnelly, Christopher J.
Accesso ente SpringerLink (Online service)
ISBN 9783319896892
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto RNA Metabolism in Neurodegenerative Diseases -- Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes -- RNA Editing Deficiency in Neurodegeneration -- RNA Nucleocytoplasmic Transport Defects in Neurodegenerative Diseases -- RNA Degradation in Neurodegenerative Disease -- RNP Assembly Defects in Spinal Muscular Atrophy -- Stress Granules and ALS: A Case of Causation or Correlation? -- Deregulation of RNA Metabolism in Microsatellite Expansion Diseases -- Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD -- Senataxin, a Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From Normal Function to Pathological Roles in Motor Neuron Disease and Cerebellar Degeneration -- Lost in Translation – Evidence for Protein Synthesis Deficits in ALS/FTD and Related Neurodegenerative Diseases.
Record Nr. YALE-13655240
Materiale a stampa
Lo trovi qui: Yale University
Neuropharmacology of New Psychoactive Substances (NPS) [electronic resource] : The Science Behind the Headlines / edited by Michael H. Baumann, Richard A. Glennon, Jenny L. Wiley
Neuropharmacology of New Psychoactive Substances (NPS) [electronic resource] : The Science Behind the Headlines / edited by Michael H. Baumann, Richard A. Glennon, Jenny L. Wiley
Estensione 1 online resource (VIII, 380 p.) 81 illus., 13 illus. in color.
Disciplina 612.8
Accesso persona Baumann, Michael H.
Glennon, Richard A.
Wiley, Jenny L.
Accesso ente SpringerLink (Online service)
ISBN 9783319524443
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. YALE-13855001
Materiale a stampa
Lo trovi qui: Yale University
Techniques to Investigate Mitochondrial Function in Neurons [electronic resource] / edited by Stefan Strack, Yuriy M. Usachev
Techniques to Investigate Mitochondrial Function in Neurons [electronic resource] / edited by Stefan Strack, Yuriy M. Usachev
Estensione 1 online resource (XV, 344 p.) 74 illus., 51 illus. in color.
Disciplina 612.8
Accesso persona Strack, Stefan.editor.
Usachev, Yuriy M.editor.
Accesso ente SpringerLink (Online service)
ISBN 9781493968909
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Three-Dimensional Reconstruction of Neuronal Mitochondria by Electron Tomography -- Measuring Mitochondrial Shape with ImageJ -- Live Imaging Mitochondrial Transport in Neurons -- Techniques to Investigate Bioenergetics of Mitochondria -- Respirometry in Neurons -- Measuring ATP in Axons with FRET -- Characterizing Metabolic States using Fluorescence Lifetime Imaging Microscopy (FLIM) of NAD(P)H -- Techniques for Simultaneous Mitochondrial and Cytosolic Ca2+ Imaging in Neurons -- Live Imaging of Mitochondrial ROS Production and Dynamic Redox Balance in Neurons -- Monitoring of Permeability Transition Pore Openings in Isolated Individual Brain Mitochondria -- Examination of Mitochondrial Ion Conductance by Patch Clamp in Intact Neurons and Mitochondrial Membrane Preparations -- Monitoring of Permeability Transition Pore Openings in Mitochondria of Cultured Neurons -- Protocols for Assessing Mitophagy in Neuronal Cell Lines and Primary Neurons -- Examining Mitochondrial Function at Synapses In Situ -- Proteomic Analysis of Neuronal Mitochondria -- Measuring Mitochondrial Pyruvate Oxidation.
Record Nr. YALE-13712838
Materiale a stampa
Lo trovi qui: Yale University
Synapse Development [electronic resource] : Methods and Protocols / edited by Alexandros Poulopoulos
Synapse Development [electronic resource] : Methods and Protocols / edited by Alexandros Poulopoulos
Estensione 1 online resource (XI, 372 p.) 79 illus., 67 illus. in color.
Disciplina 612.8
Accesso persona Poulopoulos, Alexandros.editor.
Accesso ente SpringerLink (Online service)
ISBN 9781493966882
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto A Cell Culture System to Investigate the Presynaptic Control of Subsynaptic Membrane Differentiation at the Neuromuscular Junction -- Co-Culture Synaptogenic Assay: A New Look at Fluorescence Reporters and Technological Devices -- Synaptogenic Assays Using Neurons Cultured on Micropatterned Substrates -- Monitoring Synapses Via Trans-Synaptic GFP Complementation -- Generation of Spinal Motor Neurons from Human Pluripotent Stem Cells -- Biochemical Purification of Binding Partners of Synaptic Scaffold Proteins -- In Situ Protein Binding Assay Using Fc-Fusion Proteins -- ation Microscopy for the Investigation of Synaptic Structure and Function -- 3D dSTORM Imaging of Fixed Brain Tissue -- Photomarking Relocalization Technique for Correlated Two-Photon and Electron Microcopy Imaging of Single Stimulated Synapses -- 3D Analysis of Synaptic Ultrastructure in Organotypic Hippocampal Slice Culture by High-Pressure Freezing and Electron Tomography -- Analyzing Endosomal Docking, Fusion, Sorting, and Budding Mechanisms in Isolated Organelles -- Concurrent Imaging of Receptor Trafficking and Calcium Dynamics by Spinning Disk Confocal Microscopy -- Imaging Activity-Dependent Signaling Dynamics at the Neuronal Synapse Using FRET-Based Biosensors -- Analyzing Structural Plasticity of Dendritic Spines in Organotypic Slice Culture -- Using Fluorescent Markers to Estimate Synaptic Connectivity In Situ -- Dual Anterograde and Retrograde Viral Tracing of Reciprocal Connectivity -- Mapping Synaptic Inputs of Developing Neurons Using Calcium Imaging -- Monosynaptic Tracing in Developing Circuits Using Modified Rabies Virus.
Record Nr. YALE-13712889
Materiale a stampa
Lo trovi qui: Yale University
Psychoneuroimmunology [electronic resource] : Methods and Protocols / edited by Qing Yan.
Psychoneuroimmunology [electronic resource] : Methods and Protocols / edited by Qing Yan.
Edizione [2nd ed. 2018.]
Estensione 1 online resource (XI, 381 p.) 41 illus., 27 illus. in color.
Disciplina 612.8
Accesso persona Yan, Qing.editor.
Accesso ente SpringerLink (Online service)
ISBN 9781493978281
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Stress and Systemic Inflammation: Yin-Yang Dynamics in Health and Diseases -- Intersections between Neuroimmune-Microbiota -- Psychoneuroimmunology: The Experiential Dimension -- Ecological Context and Human Variation: Applying the Principles of Biological Anthropology to Psychoneuroimmunology -- Neuroimmune Imbalances and Yin-Yang Dynamics in Stress, Anxiety, and Depression -- Increasing Resilience to Traumatic Stress: Understanding the Protective Role of Well-Being -- Exploring the Diagnostic Potential of Immune Biomarker Co-Expression in Gulf War Illness -- Breaking Away: The Role of Homeostatic Drive in Perpetuating Depression -- Neuroimmune Mechanisms of Depression in Adults with Heart Failure -- How To Monitor the Neuroimmune Biological Response in Patients Affected by Immune Alteration-Related Systemic Diseases -- Application of Chemogenetics and Optogenetics to Dissect Brain-Immune Interactions -- Psychoneuroimmunology and Natural Killer Cells: The Chromium Release Whole Blood Assay -- Mouse Testing Methods in Psychoneuroimmunology 2.0: Measuring Behavioral Responses -- The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions -- PET Imaging in Psychoneuroimmunology Research -- The Vaccination Model in Psychoneuroimmunology Research: A Review -- Measuring Vaccine Responses in the Multiplex Era -- Sculpting the Sculptors: Methods for Studying the Fetal Cholinergic Signaling on Systems and Cellular Scales -- Perinatal Psychoneuroimmunology: Protocols for the Study of Prenatal Stress and Its Effects on Fetal and Postnatal Brain Development.
Record Nr. YALE-13713061
Materiale a stampa
Lo trovi qui: Yale University
Neurophysiological Techniques [electronic resource] : Applications to Neural Systems / edited by Alan A. Boulton, Glen B. Baker, Case H. Vanderwolf
Neurophysiological Techniques [electronic resource] : Applications to Neural Systems / edited by Alan A. Boulton, Glen B. Baker, Case H. Vanderwolf
Estensione 1 online resource (XIII, 377 p.) 19 illus.
Disciplina 612.8
Accesso persona Boulton, Alan A.editor.
Baker, Glen B.editor.
Vanderwolf, Case H.editor.
Accesso ente SpringerLink (Online service)
ISBN 9781592596201
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Extracellular Single-Unit Recording Methods -- Techniques to Study Spinal-Cord, Peripheral Nerve, and Muscle Activity in Freely Moving Animals -- Human Evoked Potentials -- Field Potentials in the Central Nervous System -- Computer Techniques in Neurophysiology.
Record Nr. YALE-13710987
Materiale a stampa
Lo trovi qui: Yale University
Animal Models of Neurological Disease, II [electronic resource] : Metabolic Encephalopathies and the Epilepsies / edited by Alan A. Boulton, Glen B. Baker, Roger F. Butterworth
Animal Models of Neurological Disease, II [electronic resource] : Metabolic Encephalopathies and the Epilepsies / edited by Alan A. Boulton, Glen B. Baker, Roger F. Butterworth
Estensione 1 online resource (XVIII, 373 p.)
Disciplina 612.8
Accesso persona Boulton, Alan A.editor.
Baker, Glen B.editor.
Butterworth, Roger F.editor.
Accesso ente SpringerLink (Online service)
ISBN 9781592596270
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Experimental Models of Human Stroke -- Animal Models of Brain Hypoxia -- Animal Models of the Wernicke-Korsakoff Syndrome -- Chemically Induced Models of Seizures -- The Kindling Model of Epilepsy -- Genetically Based Animal Models of Seizures -- Animal Models of Hepatic Encephalopathies -- Animal Models for Reye’s Syndrome -- Animal Models of Niacin-Nicotinamide Deficiency -- Pyridoxine Deficiency -- Animal Models of Hereditary Hyperammonemias.
Record Nr. YALE-13710995
Materiale a stampa
Lo trovi qui: Yale University
Patch-Clamp Applications and Protocols [electronic resource] / edited by Alan A. Boulton, Glen B. Baker, Wolfgang Walz
Patch-Clamp Applications and Protocols [electronic resource] / edited by Alan A. Boulton, Glen B. Baker, Wolfgang Walz
Estensione 1 online resource (XVI, 316 p.)
Disciplina 612.8
Accesso persona Boulton, Alan A.editor.
Baker, Glen B.editor.
Walz, Wolfgang.editor.
Accesso ente SpringerLink (Online service)
ISBN 9781592596317
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Technology of Patch- Clamp Electrodes -- Whole-Cell Patch-Clamp Recordings -- Pressure/Patch-Clamp Methods -- Cell-Free Ion-Channel Recording -- Perfusion of Patch Pipets -- Concentration Clamp Technique -- Perforated Patch-Clamp Technique -- The Loose Patch Voltage Clamp Technique -- Patch-Clamp Recording and RT-PCR on Single Cells -- Patch-Clamp Technique in Brain Slices -- Xenopus Oocyte Microinjection and Ion-Channel Expression.
Record Nr. YALE-13711043
Materiale a stampa
Lo trovi qui: Yale University